Antibiotics Not Linked to Cognitive Decline in Older Adults – Study

Korede Abdullah in Lagos

A new study published in Neurology, the medical journal of the American Academy of Neurology, has found that antibiotic use is not associated with an increased risk of cognitive impairment and dementia in healthy older adults.

The study, which followed over 13,500 participants for five years, provides reassurance for older adults who may be concerned about the potential impact of antibiotics on their cognitive health.

The researchers used data from the ASPirin in Reducing Events in the Elderly (ASPREE) study, a randomized trial of community-based older adults in Australia.

They found that 63% of participants had taken antibiotics at least once during the two-year follow-up period, but that this did not increase their risk of developing dementia or cognitive impairment.

According to Steve Allder, MD, “The study clearly shows that antibiotic use does not increase the risk of cognitive impairment or dementia for healthy older adults. The results are encouraging, particularly given the prior concerns surrounding antibiotics and gut health.”

Allder emphasized that antibiotics should still be used responsibly and only as prescribed by healthcare professionals.

The study’s findings were echoed by Clifford Segil, DO, a neurologist at Providence Saint John’s Health Center in Santa Monica, CA.

“Recurrent infections requiring antibiotics indicate underlying illnesses, and infrequent antibiotic use should not be a scary thing to do in old age or when young,” he said. Segil also emphasized the importance of treating infections promptly to prevent confusion and delirium.

Both Allder and Segil provided additional advice for reducing dementia risk, including engaging in mental stimulation, staying socially connected, maintaining a healthy diet, and prioritizing sleep and stress management.

By following these tips and using antibiotics responsibly, older adults can reduce their risk of cognitive decline and dementia.

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